The Sleep Game Changers

October 2025

Sleep is one of the most important components of health! Yet, many of us don’t prioritise it nearly as much as we should. A poor sleep can increase insulin resistance, lower testosterone, impair the immune system, contribute to brain damage, speed up the aging process and increase the risk of depression. However, simply getting to bed at the right time can be a game changer when it comes to getting a good nights sleep.

The golden hours

According to circadian biology research, when it comes to sleep, the golden hours are between 10pm and 2am. During these hours, the following processes occur:

  • 10pm - melatonin peaks and the immune system activates

  • 11pm - liver detox begins and growth hormone surges

  • 12pm - deep sleep peaks and intensive brain washing occurs

  • 1am - cellular repair is at its maximum and DNA restoration occurs

  • 2am - deepest detox occurs and toxin elimination is completed

These four hours are the most valuable hours of sleep that you will get during the night. Your liver performs 80% of its detoxification, your cells repair, your immune system targets cancer cells, your gut produces neurotransmitters, your muscles rebuild and your hormones reset.

Sleeping from 10am to 2am can be more beneficial than sleeping from 2am to 10am. As you can see, it pays to be in bed early!

The brain washing system

During deep sleep, your brain cells shrink by 60%, creating channels between them. Cerebrospinal fluid (the fluid around your brain and spinal cord) rushes through these channels, flushing out the toxins that have accumulated during the day.

Research from the University of Rochester demonstrated that the following waste products get flushed during deep sleep:

  • Beta-amyloid protein - the protein that forms Alzheimer’s plaques

  • Tau proteins - the cause of neurofibrillary tangles in dementia

  • Alpha-synuclein - the protein that causes Parkinson’s disease

  • Metabolic waste - byproducts of cellular energy production

  • Damaged neurons - cells killed by oxidative stress

  • Heavy metals - including mercury, aluminium and lead

  • Inflammatory markers - cytokines that cause brain fog

  • Stress hormones - excess cortisol and adrenaline

The amount of sleep matters

The brain washing process requires 4-6 sleep cycles to work properly. Each sleep cycle is approximately 90 minutes, which means you need 7-8 hours of quality sleep for complete detoxification to occur.

Not getting enough sleep, taking sleeping pills or drinking alcohol prior to bed can all impact the brains ability to detoxify during sleep. If you wake at 6am, you need to be asleep around 10pm so that you maximise the golden hours, as well as get enough sleep to allow your brain to detox fully.

The daily habit hacks

Studies show that the following daily protocol increases deep sleep by an average of 45 minutes per night:

  • No caffeine after 12pm - caffeine has a half life of six hours

  • No alcohol within three hours of bed - blocks REM and deep sleep

  • No food within three hours of bed - digestion prevents deep sleep

  • Get to bed by 10pm - maximise the liver detox window

  • Wake at the same time each day - trains your circadian rhythm

The 4-8-7 knockout breath

Do you struggle to fall asleep? I know I do. It can be incredibly frustrating, especially if you have an early start the next day. The 4-8-7 knockout breath is a technique used by military pilots in combat zones to help them fall asleep.

Inhale through your nose for 4 counts

Hold your breath for 7 counts

Exhale through your mouth for 8 counts

Repeat this cycle 4 times

Put your the phone away, set your bedroom temperature to 18-20 degrees, take your supplements and get into bed early. You’ll wake up feeling refreshed and full of energy and vitality. Deep sleep isn’t a luxury, it’s a necessity for your long-term health and wellbeing.

Prioritise it today and your body will thank you for it tomorrow!

References

https://www.science.org/doi/10.1126/science.1241224?utm_source=lifeuntox.com&utm_medium=newsletter&utm_campaign=deep-sleep-your-body-s-nightly-detox-system&_bhlid=a7ad7682c278723bc79d6275c45a36e00ab55fa3